HEREDITARY GINGIVAL FIBROMATOSIS PDF

Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth. HGF is characterized as a . Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported . Hereditary gingival fibromatosis can occur as an isolated. Mutation in SOS1, son-of-sevenless gene, is thought to be responsible for hereditary gingival fibromatosis. This report shows a case of.

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Panoramic radiograph showing normal development of permanent teeth and missing fibbromatosis maxillary right first and left second premolars. There was no associated bleeding or pain noted with growth. It may develop as an isolated disorder but can feature along with a syndrome.

Case Reports in Dentistry

Aesthetic and functional compromises often demand surgical intervention; although recurrence cannot be predicted. This report presents the clinical fibromatoeis and the management of 12 year old female child with a severe variety of HGF.

The case presented in this paper differs from previous reports since she needed combined orthodontic and orthognathic treatment because of severe skeletal discrepancies of the jaws.

Role of c-myc proto-oncogene in the proliferation of hereditary gingival fibromatosis fibroblast. Hereditary gingival fibromatosis Synonyms Autosomal dominant gingival hyperplasia Classification and external resources Specialty oral and maxillofacial surgery ICD – 10 K Open in a separate window.

Am J Hum Genet ; This is an open-access article distributed under the heredjtary of the Creative Commons Attribution-Noncommercial-Share Alike 3. In the patient presented, deferring orthodontic treatment until growth potential decreases and correcting the problem through combined orthodontic and orthognathic procedures were planned.

It can cover teeth in various degrees, and can lead to aesthetic disfigurement. The patient is planned for surgical removal of lesion by CO 2 laser quadrant gingivectomy.

Oral and systemic findings in siblings. In the second case, the external bevel technique allowed the gingivectomy and gingivoplasty to be performed without raising a flap, avoiding the need for suture, and was more conservative towards the developing DGJ.

Cementicle Cementoblastoma Gigantiform Cementoma Eruption cyst Epulis Pyogenic granuloma Congenital epulis Gingival enlargement Gingival cyst of the adult Gingival cyst of the newborn Gingivitis Desquamative Granulomatous Plasma cell Hereditary gingival fibromatosis Hypercementosis Hypocementosis Linear gingival erythema Necrotizing periodontal diseases Acute necrotizing ulcerative gingivitis Pericoronitis Peri-implantitis Periodontal abscess Periodontal trauma Periodontitis Aggressive As a manifestation of systemic disease Chronic Perio-endo lesion Teething.

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View at Google Scholar J. Hereditary gingival fibromatosis HGF is a rare benign, slowly progressive, non-inflammatory fibrous hyperplasia of the maxillary and mandibular gingivae that generally occurs with the eruption of the permanent or more rarely the primary dentition or even at birth.

The maxillary teeth were not all visible except in right and left posterior region. Received Dec 4; Accepted Jan 7.

Hereditary gingival fibromatosis – Wikipedia

Severe hperplasia can result in restricted movements of the tongue, speech impediments, difficulty with mastication, and can prevent normal closure of lips.

Am J Med Genet ; The documents contained in this web site are presented for information purposes only. The patient noted the growth 3 years back, since then it was progressively increasing in size causing inadequate lip apposition and poor esthetic.

CASE REPORT A 12 years old female child reported to the Department of Periodontics, Government Dental College and Hospital, Nagpur complaining of gingival swelling, which caused severe compromise in her speech, mastication and aesthetics gongival led to considerable disfigurement of her facial profile, owing to the severity of gingival enlargement.

Regarding the higher rate of recurrence in children and teenagers compared to adults [ 18 ], we found it better to delay surgical intervention gingivectomy until commencement of the presurgical orthodontic phase and planned periodic visits to monitor eruption of remained permanent fibroamtosis.

Hereditary gingival fibromatosis

This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The excess gingival tissue, in this non-syndromic case was removed by conventional gingivectomy using local as well as general anaesthesia. Please review our privacy policy. In the current periodontal diseases and conditions classification developed by Armitage inHGF is one of the categories of Gingival lesions of genetic origin in the Gingival Diseases section 1 – 5.

Hereditary gingival fibromatosis Flbromatosis is a rare condition which manifests itself by an enlarged gingival tissue covering teeth to various extents. The extent and severity of fibromatosis in this case has covered almost all teeth thereby causing difficulty in gibgival and speech.

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Hence, it was concluded that the presence of dentition is necessary for HGF to develop. The degrees of gingival enlargement show both intra- and interindividual variations. How to cite this article: The histological findings are nonspecific and include acanthotic and hyperkeratotic epithelium with elongated rete ridges deeply extended to a relative avascular connective tissue with hereditzry arranged collagen fibromatoosis and numerous fibroblasts [ 114 ].

Hereidtary examination [ Figure 2 ] showed a massive, generalized multinodular growth covering both maxillary and mandibular arch completely causing incompetent everted lips and a convex profile. Hereritary examination of maxilla [ Figure 3 ] revealed a gross generalized growth of gingiva completely covering the maxillary teeth extending from right maxillary tuberosity to left tuberosity region.

Autosomal dominant forms of gingival fibromatosis, which are usually non-syndromic, have been genetically linked to the chromosome 2pp22 and 5qq Footnotes Source of Support: Patient was advised for incisional biopsy. Increase proliferation, collagen and fibronectin production by hereditary gingival fibromatosis fibroblast. Since the dentition showed normal development and heeeditary eruption of permanent teeth was not affected by the condition, repeated gingivectomies were not included in the treatment plan.

Am J Hum Genet. National Center for Biotechnology InformationU.

Hereditary gingival fibromatosis: Characteristics and treatment approach

This page was last edited on 20 Decemberat However, this technique lengthened the operation time fibromatosiss. The HGF is a rare condition of the gingival tissues characterized by enlargement of free and attached gingivae.

The treatment consists of surgical excision of the enlarged tissue; often in a series of gingivectomies, that should be complemented by an effective program of oral hygiene. Unilateral gingival fibromatosis with localised aggressive periodontitis involving first molars: The enlarged gingival tissue appears firm and pink with exaggerated stippling. Most recent methods of treatment take the form of surgeries such as oral prophylaxisfollowed by post-surgical therapies to monitor, provide proper oral hygiene, and correct the deformity.

Footnotes Source of Support: It has characteristic smooth to pebbled surface with little tendency to bleed.

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